منابع مشابه
Tritiated Digoxin XVIII
Tritiated digoxin turnover studies were performed in nine children aged 4 days to 7 years. Mean serum turnover time was 32.5 (range 18-48) hours, and the 3-day urine and stool excretion was 55% of the total dose administered. These findings are quite similar to those observed in adults and indicate that the larger doses of digoxin required for digitalization in infants are not accompanied by in...
متن کاملThe Excretion of Tritiated Digoxin
Six normal human volunteers as renal transplant donors were given 33H-digoxin before and again after unilateral nephrectomy. The serum digoxin concentration was modestly increased following nephrectomy, the serum digoxin half-time was slightly prolonged, and total digoxin excretion for the group was reduced by only 6.4% during a 7-day study. Four of the six patients studied before and after uni...
متن کاملStudies with tritiated digoxin in anephric human subjects.
Tritiated digoxin was given to 11 patients when anephric prior to renal transplant. These patients exhibited high digoxin serum levels, increased digoxin serum half-times, and reduced excretion of digoxin compared to those of patients with congestive heart failure and normal BUN and are similar in this respect to patients with severe compromise of renal function. The stool excretion of digoxin ...
متن کاملInfluence of potassium depletion on myocardial concentration of tritiated digoxin.
The influence of potassium deficiency on myocardial H-digoxin concentration in the mouse was studied. Tritiated digoxin, 400 /Ag/kg, was injected intraperitoneally into mice, which were killed at varying time intervals, and the "H-digoxin was extracted. One-half of the mice were made potassium deficient by a diet free of potassium. In control animals, myocardial H-digoxin was maximal by 30 min ...
متن کاملTritiated digoxin excretion of patients following renal transplantation.
Four patients with a single allografted kidney were given 1.0 mg of tritiated digoxin intravenously. Compared with patients with two normally functioning kidneys, these patients cxhibited increased digoxin serum levels, modestly reduced renal excretion, and increased stool excretion of digoxin during a 7-day study. When administration of digoxin is indicated for a patient with a renal transplan...
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ژورنال
عنوان ژورنال: Circulation
سال: 1970
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.42.5.867